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AssigneeFuture University In Egypt
InventorsFatma Samir Abd El-Salam El-Sebaie, Seham Abd Elkhalek Elkheshen, Azza Ahmed Mohamed Mahmoud, Nermeen Adel Ahmed Elkasabgy, Emad Basalious Bashir Basalious, Amany Abdel Monem Mostafa Abdel Rahman, Mohammed Said Mostafa Amer
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A pharmaceutical composition capable of forming free burst release effect in-situ forming implant useful for injection inside bone injuries without surgery is provided. This pharmaceutical composition includes; biodegradable polymer, selective estrogen receptor modulator, organic solvent and liquid lipid, solidifies upon contacting with the surrounding medium and form solid implant with compact framework by in-situ phase separation method to deliver the selective estrogen receptor modulator. This compact framework restores the porous structure of the implant by time which is essential in promoting bone healing.
An In-situ forming implant formulation comprising:
Dependencies are inferred from the claim text.