Micronized lipids
AssigneeMCAL Therapeutics Inc.
InventorThomas Gadek
Life of this patent
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Abstract
The present invention relates to drug delivery vehicles comprising micronized particles that include an active lipid agent, and in particular to micronized lipid particles that comprise an ether lipid such as sn-1-O-eicosanyl-sn-2-palmitoyl-glycerol and its isomers.
Claims31
A drug delivery vehicle comprising crystalline solid non-polar lipid particles having an average particle size of less than 50 microns, the particles comprising an active agent other than the lipids forming the crystalline solid non-polar lipid particles, wherein the lipids forming the crystalline solid non-polar lipid particles comprise lipids selected from the group consisting of:
- wherein
- R1 is an unsubstituted C6 to C30 alkyl or alkenyl;
- R2 is an unsubstituted C5 to C29 alkyl or alkenyl;
- and
- R3 is a hydrogen;
- wherein
- R1 is a hydrogen;
- R2 is an unsubstituted C5 to C29 alkyl or alkenyl;
- and
- R3 is an unsubstituted C6 to C30 alkyl or alkenyl;
- wherein
- R1 is an unsubstituted C6 to C30 alkyl or alkenyl;
- R2 is an unsubstituted C5 to C29 alkyl or alkenyl;
- and
- R3 is a hydrogen,
- wherein
- R1 is an unsubstituted C6 to C30 alkyl or alkenyl;
- R2 is a hydrogen;
- and
- R3 is an unsubstituted C5 to C29 alkyl or alkenyl;
- wherein
- R1 is an unsubstituted C5 to C29 alkyl or alkenyl;
- R2 is a hydrogen;
- and
- R3 is an unsubstituted C6 to C30 alkyl or alkenyl;
- and
- wherein
- R1 is an unsubstituted C6 to C30 alkyl or alkenyl;
- R2 is a hydrogen;
- and
- R3 is an unsubstituted C5 to C29 alkyl or alkenyl.
Dependencies are inferred from the claim text.