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US 12,214,079 B2Granted
Micronized lipids
AssigneeMCAL Therapeutics Inc.
InventorThomas Gadek
Life of this patent
Estimating the term…
Abstract
The present invention relates to drug delivery vehicles comprising micronized particles that include an active lipid agent, and in particular to micronized lipid particles that comprise an ether lipid such as sn-1-O-eicosanyl-sn-2-palmitoyl-glycerol and its isomers.
Claims30
A lipid particle composition comprising crystalline solid non-polar lipid particles having an average particle size of less than 50 microns stably suspended in a buffered aqueous vehicle suitable for topical administration, wherein the crystalline solid non-polar lipid particles comprise lipids selected from the group consisting of:
- wherein
- R1 is an unsubstituted C6 to C30 alkyl or alkenyl;
- R2 is an unsubstituted C5 to C29 alkyl or alkenyl;
- and
- R3 is a hydrogen;
- wherein
- R1 is a hydrogen;
- R2 is an unsubstituted C5 to C29 alkyl or alkenyl;
- and
- R3 is an unsubstituted C6 to C30 alkyl or alkenyl;
- wherein
- R1 is an unsubstituted C6 to C30 alkyl or alkenyl;
- R2 is an unsubstituted C5 to C29 alkyl or alkenyl;
- and
- R3 is a hydrogen
- wherein
- R1 is an unsubstituted C6 to C30 alkyl or alkenyl;
- R2 is a hydrogen;
- and
- R3 is an unsubstituted C5 to C29 alkyl or alkenyl;
- wherein
- R1 is an unsubstituted C5 to C29 alkyl or alkenyl;
- R2 is a hydrogen;
- and
- R3 is an unsubstituted C6 to C30 alkyl or alkenyl;
- and
- wherein
- R1 is an unsubstituted C6 to C30 alkyl or alkenyl;
- R2 is a hydrogen;
- and
- R3 is an unsubstituted C5 to C29 alkyl or alkenyl.
28 more elements
Dependencies are inferred from the claim text.