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US 12,214,043 B2Granted
Therapeutic nanomaterials
OwnerYupeng Chen, Jinhyung Lee +1inventors
InventorsYupeng Chen, Jinhyung Lee, Wuxia Zhang
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Abstract
Disclosed herein is a delivery vehicle based on DNA-inspired Janus based nanotubes (JBNTs) for anti-viral treatment. The nanoparticles (NPs) are based the JBNTs conjugated with targeting moieties such as small molecules, aptamers, and peptides.
Claims2
A composition comprising a compound of Formula (I):
- or a pharmaceutically acceptable salt thereof, wherein:
- R1 is H or CH3;
- R2 is (CH2)j, (CH2CH2O)k or (CH2CH2NH)m;
- j, k, and m are the chemical subscripts for the moieties listed in R2 and each it independently represents 0-200 of the repeating moieties;
- L is absent;
- and
- X is folic acid
- wherein the composition has a pH of about 1 to about 10.
5 more elements
Dependencies are inferred from the claim text.