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US 12,214,042 B2Granted
Method for stabilization and delivery of therapeutic molecules
AssigneeNayan Patel
InventorsNayan Patel, Chinh Tran
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Abstract
A method of treatment is disclosed, comprising administering a composition of Cyclodextrin and reduced, nanonized L-Glutathione to a patient in need of treatment, wherein the L-Glutathione molecule is non-acetylated, non-Esterified, and non-fatty acid attached.
Claims19
A composition comprising:
- an inclusion complex comprising reduced glutathione and gamma cyclodextrin;
- wherein the reduced glutathione is non-esterified, non-acetylated, and non-fatty acid attached;
- wherein the molar ratio of the reduced glutathione to the gamma cyclodextrin is between about 4:1 and 13:1;
- wherein ultrasonic waves nanonize the pH stabilized inclusion complex into nanoparticles;
- wherein the nanoparticles have a particle size range between 2 to 160 nanometers;
- and
- wherein the composition is configured for topical administration.
4 more elements
Dependencies are inferred from the claim text.