Back to results
US 12,214,038 B2Granted
Compositions and methods for cancer immunotherapy
AssigneeThe Trustees of the University of Pennsylvania
InventorAndrea Facciabene
Life of this patent
Estimating the term…
Abstract
The invention provides compositions and methods for cancer immunotherapy. Specifically, the invention provides an antigen-presenting cell, for example, a dendritic cell that comprises a tumor mitochondrial molecule or a tumor mitochondrial molecule derived from tumor mitochondrial protein lysate or a specific mitochondria derived protein of mitochondrial protein lysate as antigen source.
Claims14
A tumor-specific immunogenic composition comprising:
- an antigen-presenting cell pulsed with a tumor mitochondrial protein lysate from a renal cancer or a liver cancer, and wherein said antigen-presenting cell is a dendritic cell.
Dependencies are inferred from the claim text.