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AssigneeSanofi Pasteur Limited
InventorsStephen Anderson, Simon Delagrave, John Hamberger, Qinglian Li, Sophia Mundle, Nausheen Rahman
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The present disclosure relates to liquid and dried compositions comprising a live, attenuated or genetically modified herpesvirus and methods of preparing such compositions, in one aspect, the composition comprises at least two or more pharmaceutically acceptable excepients, at least one of which is histidine and at least one of which is a sugar or sugar alcohol. The compostions retain a sufficiently high infectious titre following storage or large-scale manufacturing steps, such as lyophilization.
A method of manufacturing a dried composition comprising a live, attenuated or genetically modified herpesvirus, the method comprising:
A method of manufacturing a dried composition comprising a live, attenuated or genetically modified herpesvirus, the method comprising:
Dependencies are inferred from the claim text.