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US 12,214,017 B2Granted
GLP-1 compositions and uses thereof
AssigneeNovo Nordisk A/S
InventorsEva Horn Moeller, Michael Duelund Soerensen, Joakim Lundqvist
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Abstract
The present invention relates to pharmaceutical compositions of the GLP-1 peptide semaglutide comprising no more than 0.01% (w/w) phenol, their preparation, kits comprising such compositions as well as uses thereof.
Claims9
A liquid pharmaceutical composition comprising:
- semaglutide;
- wherein said composition
- (a) does not contain phenol;
- and
- (b) is administered parenterally;
- and
- (c)(i) is an aqueous solution comprising at least 60% (w/w) water or (ii)
- further comprises one or more pharmaceutically acceptable excipients selected from the group consisting of a buffer or an isotonic agent;
- and
- wherein the semaglutide is in the range of 0.01 mg/ml-10.0 mg/ml;
- and
- wherein the pH of the composition is in between 7.0 and 7.8.
9 more elements
Dependencies are inferred from the claim text.