Coated medicinal clay compositions, pharmaceutical compositions, and delivery of cation sources and methods of use thereof

A method of treatment of a subject with a composition comprising:

• administering to a tissue, organ, or wound optionally wherein the tissue, organ, or wound comprises exudate comprising exudate therefrom of a subject in need of treatment a medicinal clay composition and at least one coating agent surrounding the medicinal clay composition, wherein the medicinal clay composition comprises a cation source and has
• a Cation Exchange Capacity of at least about greater than about 10 mEq/100 g,
• an Oxidation-Reduction Potential greater than about 250 mV,
• a pH less than about 5.0, a crystalline composition comprising smectite, illite,
• and/or illite-smectite that is at least about 40 wt-% of the medicinal clay composition,
• and less than 40 ppm heavy metal contaminants,
• and wherein the at least one coating agent comprises a nonionic block Ethylene oxide-propylene oxide (EO-PO) copolymer with an average molecular weight of from about 5,000 to about 20,000,
• wherein said coating agent prevents the premature activation of the medicinal clay composition by surrounding the medicinal clay composition,
• wherein the medicinal clay is activated upon contacting a water source,
• wherein the medicinal clay composition reduces the pH of the tissue or organ to less than about 4 to promote healing, and reducing microbial populations on the subject and/or removing exudate from the tissue, organ, or wound in need of treatment.