Colchicine solution
AssigneePharma-Data Research and Development Single Member S.A.
InventorsIoannis Psarrakis, Konstantinos Lioumis
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Abstract
Described is a stable buffered aqueous colchicine solution or suspension being free of benzyl alcohol, comprising colchicine, a water miscible solvent and a preservative, characterized in that the solution comprises 0.01-1.0 w/v % colchicine, 2.5-15.0 w/v % glycerol and 0.05-1 w/v % preservative, the pH of the solution or suspension being 4.5-7.0. A method for the preparation thereof is also disclosed.
Claims21
A buffered aqueous colchicine solution or suspension being free of benzyl alcohol, propylene glycol and thickener, comprising colchicine, a water miscible solvent and a preservative, wherein the solution or suspension comprises 0.02-1.0 w/v % colchicine, 2.5-15.0 w/v % glycerol and 0.05-1 w/v % preservative, the pH of the solution or suspension being 3.5-7.0.
Dependencies are inferred from the claim text.