Ablation targeting and planning system

A method performed by one or more computing systems for generating an ablation plan for an ablation procedure to be performed on a body part of a patient, the body part having an abnormal pattern of electrical activity, the method comprising:

• receiving patient data of the patient that includes a patient electrogram and a patient body part image;
• applying a mapping system to the patient electrogram to identify a source location of the abnormal pattern of electrical activity;
• applying an ablation target system to identify an ablation target within the body part based on at least some of the patient data;
• applying a parameter plan system to at least some of the patient data and the ablation target to identify an ablation plan that includes target parameter values for ablation device parameters for controlling an ablation device, the parameter plan system developed based on data that includes clinical data sets that are each derived from an electronic health record of a person of a plurality of persons already treated, each clinical data set associated with a person parameter plan of the person;
• and
• outputting an indication of the ablation target and the ablation plan;
• wherein the body part is a heart, the abnormal pattern of electrical activity is an arrhythmia, and the ablation procedure is to terminate the arrhythmia;
• wherein the parameter plan system is a parameter plan machine learning (ML) model that is trained with training data that includes data of clinical data sets labeled with parameters values for ablation device parameters for controlling the ablation device;
• and
• wherein the parameter plan ML model is a composite model that includes an electrogram ML sub-model that inputs the patient electrogram of the patient and outputs a patient electrogram representation of the patient electrogram and includes a cardiac image ML sub-model that inputs a patient cardiac image of the patient and outputs a patient cardiac image representation, and a final ML sub-model that inputs the patient electrogram representation and the patient cardiac image representation and outputs parameter values.

A computing system for generating an ablation plan for a patient ablation procedure to be performed on a patient heart of a patient who has a patient arrhythmia, the computing system comprising:

• one or more computer-readable storage mediums configured to store a person data for each of a plurality of persons already treated who have had a person ablation procedure to treat a person arrhythmia, the person data including a person parameter plan, a person cardiogram, and a person ablation target, the person parameter plan including person parameter values for tunable parameters of an ablation device;
• and
• computer-executable instructions for controlling the computing system programmed to:
• access patient data of the patient that includes a patient cardiogram;
• identify a patient source location of the patient arrhythmia based on the patient cardiogram;
• apply an ablation target system to identify, based on the patient source location and the patient data, a patient ablation target within the patient heart, the ablation target system based on a plurality of combinations of a simulated source location of a simulated arrhythmia and a simulated ablation target of each of the plurality of the persons already treated, running a simulation of electrical activity of at least one person's heart of the plurality of persons already treated using a three-dimensional (3D) mesh representing the at least one person's heart that is derived from the person data of the at least one person,
• an initial portion of the simulation being run, based on the simulated source location and not based on the simulated ablation target, until the simulated arrhythmia is induced, and
• a final portion of the simulation being run, based on the simulated ablation target, to determine whether an ablation performed targeting the simulated ablation target would terminate the simulated arrhythmia originating from the simulated source location;
• apply a parameter plan system to the patient data and the patient ablation target to identify a patient parameter plan that includes patient parameter values for tunable parameters of a patient ablation device for controlling the patient ablation device, the patient parameter plan developed based on the person data of each of the plurality of persons already treated who have had a successful person ablation procedure to treat the person arrhythmia;
• send to the patient ablation device the patient ablation target and the patient parameter plan;
• and
• direct the performing of the patient ablation procedure on the patient based on the patient ablation target and the patient parameter plan;
• and
• one or more processors for controlling the computing system to execute the computer-executable instructions.

A method for treating a patient based on an ablation plan for an ablation procedure to be performed on a patient heart of the patient, the patient heart having a patient arrhythmia, the ablation plan specifying a patient ablation target and a patient parameter plan for treating the patient arrhythmia, the method comprising:

• receiving patient data of the patient that includes a patient electrogram and a patient heart image;
• identifying a patient source location of the patient arrhythmia based on the patient electrogram;
• applying an ablation target system to identify the patient ablation target within the patient heart based on at least some of the patient data and the patient source location, wherein the ablation target system identifies the patient ablation target based on similarity of the patient electrogram to mappings of simulated electrograms and simulated ablation targets of a plurality of persons already treated, wherein the mappings of simulated electrograms are generated by a plurality of combinations of a simulated source location of a simulated arrhythmia and a simulated ablation target for each of the plurality of persons already treated;
• running a simulation of electrical activity of at least one person's heart of the plurality of persons already treated using a three-dimensional (3D) mesh representing the at least one person's heart that is derived from the at least one person's heart image, wherein:
• an initial portion of the simulation of the electrical activity of the at least one person's heart is run, based on the simulated source location and not based on the simulated ablation target, until a simulated arrhythmia is induced, and
• a final portion of the simulation of the electrical activity of the at least one person's heart is run, based on the simulated ablation target, to determine whether an ablation performed on the at least one person's heart targeting the simulated ablation target would terminate the simulated arrhythmia originating from the simulated source location;
• applying a parameter plan system to at least some of the patient data and the patient ablation target to identify the patient parameter plan that includes parameter values for tunable parameters of an ablation device for controlling the ablation device, the patient parameter plan developed based on person data of the at least one person of the plurality of persons already treated, the person data of the at least one person including a person ablation target and a person parameter plan for the at least one person of the plurality of persons already treated that were successful in treating an arrhythmia;
• and
• performing the ablation procedure on the patient based on the patient ablation target and the patient parameter plan.