US 12,191,133 B2 · Mass spectrometry method for identifying and/or authenticating a sample

Abstract

The present invention relates to a method for identifying and/or authenticating a sample, comprising adding at least one chemical compound to the sample, determining a level of the at least one compound after addition to the sample; comparing the level of the at least one compound to a reference level and identifying the sample based on the comparison with the reference sample and the effect of the sample on the level of the at least one compound. The invention further relates to the use of the at least one compound in the method for identifying and/or authenticating a sample. Further, the invention relates to the use of a kit comprising the at least one compound in the inventive method. In addition, the invention relates to a composition comprising the at least one compound. Further, the invention relates to a kit comprising the compositions provided herein, e.g. for calibrating the methods provided herein and/or the instruments employed in the methods provided herein.

Claims27

Dependent claims

A method for identifying and/or authenticating a sample, wherein the method comprises the steps of:

(i) adding at least one compound to the sample, wherein the at least one compound has a variable ionization;
(ii) obtaining a mass spectrum of the at least one compound and determining a level of the at least one compound after addition to the sample;
(iii) comparing the level of the at least one compound determined in (ii) to a reference level, wherein the reference level is a level of the same compound determined after addition to a reference sample;
and
(iv) identifying the sample based on the comparison in step (iii) and the effect of the sample on the level of the at least one compound.

2 more elements

Dependencies are inferred from the claim text.

Facts

Application

17/610,010Filed 8 May 2020

Priority

EP 1917382410 May 2019

Published

US 2022/0199389 A123 Jun 2022

Granted

7 Jan 2025

Term ends

Not estimatedThe source records don’t support an estimate.

Classification10 codes

G01N 33/6848
General methods of protein analysis not limited to specific proteins or families of proteins: methods of protein analysis involving mass spectrometry
H01J 49/165
Using surface ionisation, e.g. field-, thermionic- or photo-emission: electrospray ionisation
G01N 33/94
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing:…
H01J 49/0036
Methods for using particle spectrometers: step by step routines describing the handling of the data generated during a measurement

Mass spectrometry method for identifying and/or authenticating a sample

Life of this patent

Mass spectrometry method for identifying and/or authenticating a sample

Life of this patent

Abstract

Claims27