Time-domain analysis of signals for charge detection mass spectrometry
AssigneeThe Trustees of Indiana University
InventorsMartin F. Jarrold, Daniel Botamanenko
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AssigneeThe Trustees of Indiana University
InventorsMartin F. Jarrold, Daniel Botamanenko
Estimating the term…
A charge detection mass spectrometer (CDMS) includes an electrostatic linear ion trap (ELIT), a processor, and a memory having instructions stored therein executable by the processor to (a) control the ELIT to trap an ion, (b) collect ion measurement information as the trapped ion oscillates back and forth through the ELIT, the ion measurement information including charge induced by the ion on a charge detector of the ELIT during each pass of the ion through the ELIT and timing of the induced charges relative to one another, (c) process the ion measurement information in the time-domain for each of a plurality of sequential time windows of the ion measurement information to determine a charge magnitude of the ion during each time window, and (d) determine the magnitude of charge of the trapped ion based on the charge magnitudes of each of the time windows.
A method for measuring a charge of an ion in an electrostatic linear ion trap including a charge detection cylinder positioned between two ion mirrors, in which during an ion trapping event the ion repeatedly oscillates back and forth between the two ion mirrors each time passing through and inducing a corresponding charge on the charge detection cylinder and in which an ion measurement signal including magnitudes of the induced charges and timing of the induced charges during the trapping event are recorded in an ion measurement file, the method comprising:
A charge detection mass spectrometer (CDMS), comprising:
Dependencies are inferred from the claim text.