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AssigneeBattelle Memorial Institute
InventorMark R. Wilson
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The present disclosure relates, generally, to nucleotide sequence data and, more particularly, to computer files and methods supporting forensic DNA analysis. In one illustrative embodiment, a method may comprise identifying a locus corresponding to each item of short tandem repeat (STR) profiling data stored in an existing computer file, wherein the STR profiling data stored in the existing computer file is repeat-based and/or length-based; identifying start and stop coordinates of an STR region of the corresponding locus for each item of STR profiling data stored in the existing computer file; creating an ambiguous text string corresponding to each item of STR profiling data stored in the existing computer file, wherein each ambiguous text string consists of a sequence of ambiguous characters extending from the start coordinate to the stop coordinate identified for the corresponding item of STR profiling data; and storing each ambiguous text string in a sequence-based computer file.
A method comprising:
A non-transitory computer readable medium storing sequence-based short tandem repeat (STR) profiling data for a DNA sample, the sequence-based STR profiling data comprising a plurality of ambiguous text strings each representing an STR region of a locus of the DNA sample, wherein each ambiguous text string consists of a sequence of ambiguous characters extending from a start coordinate to a stop coordinate of the STR region represented by that ambiguous text string, wherein each ambiguous character of each ambiguous text string is a text character used to represent an ambiguous base call.
A non-transitory computer readable medium storing a database of sequence-based short tandem repeat (STR) profiling data for a plurality of DNA samples, each of the plurality of DNA samples having a corresponding database record comprising a plurality of ambiguous text strings that each represent an STR region of a locus of the corresponding DNA sample, wherein each ambiguous text string consists of a sequence of ambiguous characters extending from a start coordinate to a stop coordinate of the STR region represented by that ambiguous text string, wherein each ambiguous character of each ambiguous text string is a text character used to represent an ambiguous base call.
Dependencies are inferred from the claim text.