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US 12,181,469 B2Granted
Chemical sensor, method for detecting target substance, and apparatus for detecting the same
AssigneeKabushiki Kaisha Toshiba
InventorYoshiaki Sugizaki
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Abstract
According to one embodiment, a chemical sensor for detecting a target substance in a specimen, the chemical sensor including a sensitive film, a first extracellular region peptide of a transmembrane receptor immobilized on the sensitive film, a liquid phase disposed on the sensitive film, and a second extracellular region peptide of the transmembrane receptor contained within the liquid phase.
Claims6
A chemical sensor for detecting a target substance in a specimen, the chemical sensor comprising:
- a sensitive film;
- a first extracellular region peptide of a transmembrane receptor immobilized on the sensitive film;
- a liquid phase disposed on the sensitive film;
- and
- a second extracellular region peptide of the transmembrane receptor contained within the liquid phase,
- wherein the extracellular region is an extracellular loop, and
- the first extracellular region peptide and the second extracellular region peptide contain at least a part of amino acid sequence of the extracellular loop, and are circularized.
4 more elements
Dependencies are inferred from the claim text.