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US 12,180,616 B2Granted
Thermally and dimensionally stabilized electrospun compositions and methods of making same
AssigneePoly-Med, Inc.
InventorsMichael Scott Taylor, Seth Dylan McCullen
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Abstract
Thermally stable absorbable fiber populations, i.e. fiber populations that do not undergo thermally induced crystallization, can be intermixed with thermally unstable fibers to yield a stabilizing effect without altering morphological properties of a fiber system. Via this, one may minimize thermally induced shrinkage and maintain physical properties of electrospun materials in the as-formed state.
Claims19
A thermally stable electrospun material comprising:
- a first population of fibers, the first population of fibers being thermally unstable fibers;
- a second population of fibers, the second population of fibers being thermally stable fibers;
- wherein the first population of fibers and the second population of fibers are independent from each other;
- wherein the first population of fibers and the second population of fibers are co-mingled and distributed throughout the thermally stable electrospun material in a form of a fibrous mat with randomly oriented fibers;
- wherein the thermally unstable fibers are present in the thermally stable electrospun material in an amount of 49% by weight or higher;
- wherein the thermally stable fibers are present in the thermally stable electrospun material in an amount of from 13 to 49% by weight;
- wherein the thermally stable electrospun material exhibits limited macroscopic changes in physical and mechanical properties at a temperature of about 50° C.;
- and
- wherein the thermally stable electrospun material is dimensionally stable at a temperature of about 50° C.
6 more elements
A multiple fiber population electrospun fabric in a form of a fibrous mat with randomly oriented fibers comprising:
- a first population of fibers, the first population of fibers being a thermally stable polyether-ester comprising from 13 to 49% by weight of a thermally stable electrospun material;
- a second population of fibers, the second population of fibers being a thermally unstable bioabsorbable polyester;
- wherein the first population of fibers and the second population of fibers are dispersed throughout a three-dimensional structure of the multiple fiber population electrospun fabric;
- and
- wherein the multiple fiber population electrospun fabric is dimensionally stable at a temperature of about 50° C.
2 more elements
Dependencies are inferred from the claim text.