Electrochemical oxidation of organic molecules

A method of generating an oxidized substrate comprising:

• contacting an anode including an oxygen atom transfer epoxidation catalyst composition with a substrate, the oxygen atom transfer epoxidation catalyst composition including single atoms of one element of Re, Ir, Pt, Au, Ru, Rh, or Pd supported on a nanostructured material containing an oxide or metal nanoparticle including Ti, Cr, Mn, Co, Ni, Cu, or Zn;
• contacting the anode with a direct oxygen atom source;
• applying a voltage to the anode and a cathode to produce an oxidized substrate;
• wherein the cathode includes a hydrogen generation catalyst;
• and generating an epoxide and hydrogen gas.