Gene signatures for the prediction of prostate cancer recurrence
AssigneeBracco Imaging S.P.A.
InventorsAndrea Ferraris, Erika Reitano, Alessandro Maiocchi
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Abstract
Disclosed are gene signatures and methods for predicting the recurrence of prostate cancer in prostatectomized subjects. Other objectives of the invention are assay devices and kits for determining the expression levels of specific gene sets correlated to prostate cancer recurrence.
Claims11
An assay device comprising an array consisting of multiple polynucleotide probes complementary and/or hybridizable to the mRNAs of ACADVL, CARHSP1, CNTNAP1, DNASE1L2, RNF103, SEZ6L, SLC22A6, UGGT2, WDR52, and optionally one or more selected from ATP5D, C14orf109, CCDC144A, CDH15, CELSR3, DDX5, EHD4, EPHB3, LOC100508936, PABPC1, PIP4K2C, and PLCG1 genes, wherein the multiple polynucleotide probes are immobilized on a solid support.
Dependencies are inferred from the claim text.