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US 12,180,464 B2Granted
Microbial compositions and methods of use for canine enteropathy and dysbiosis
AssigneeNative Microbials, Inc.
InventorsMallory Embree, Grant Gogul, Fan Yang
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Abstract
The disclosure relates to isolated microorganisms—including novel strains of the microorganisms—microbial ensembles, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial compositions, and compositions comprising the same, in methods for treating or preventing gastrointestinal enteropathy or dysbiosis in canines. In particular aspects, the disclosure provides methods of treating or preventing morbidity and mortality caused by GI pathogenesis or autoimmunity.
Claims18
A composition comprising:
- (a) a purified population of bacteria comprising:
- (i) a bacterium comprising a 16S nucleic acid sequence sharing at least 99.5% sequence identity to SEQ ID NO:
- 19;
- (ii) a bacterium comprising a 16S nucleic acid sequence sharing at least 99.5% sequence identity to SEQ ID NO:
- 172;
- and
- (iii) optionally, a bacterium comprising a 16S nucleic acid sequence sharing at least 99.5% sequence identity to SEQ ID NO:
- 326;
- and
- (b) one or more carriers suitable for canine administration;
- wherein the bacteria in the composition are lyophilized;
- and wherein the bacteria present in the composition are in an amount effective to improve one or more traits in a canine administered the composition.
9 more elements
Dependencies are inferred from the claim text.