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US 12,180,266 B2Granted
Modified haemoglobin proteins
AssigneeUniversity of Essex Enterprises Limited
InventorsChris E. Cooper, Brandon Reeder, Gary Silkstone
Life of this patent
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Abstract
The present invention relates to modified proteins e.g. oxygen-carrying proteins, with improved or enhanced, in comparison to a reference protein, reduction of a metal ion associated with the modified protein. The present invention also relates to methods of using such modified proteins and compositions comprising such proteins e.g. in therapy.
Claims8
A human hemoglobin protein comprising at least one modified human hemoglobin beta or gamma chain subunit, wherein:
- the beta chain subunit comprises SEQ ID NO:9 or 10 or the gamma chain subunit comprises SEQ ID NO:13 or 17.
Dependencies are inferred from the claim text.