Utility of nematode small molecules
AssigneesCalifornia Institute of Technology, Boyce Thompson Institute for Plant Research, Inc.
InventorsAndrea Choe, Paul W. Sternberg, Frank C. Schroeder, Stephan H. Von Reuss
Life of this patent
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Abstract
The present invention relates to methods of treating immune disorders and/or inflammation using certain modulator compounds. In one embodiment, the present invention provides a method of treating an immune and inflammatory disorders disorder by administering a composition comprising a therapeutically effective dosage of an ascaroside compound, or a mixture of ascaroside compounds, or a mixture containing at least one ascaroside.
Claims20
A pharmaceutical composition comprising a compound selected from the group consisting of ascr #1, ascr #3, ascr #7, ascr #8, ascr #9, and ascr #10;
- and a sugar, a nucleobase, a fatty acid, and/or an amino acid, in a dosage form formulated for alleviating an inflammatory or immune disorder, wherein the pharmaceutical composition further comprises a pharmaceutically acceptable carrier.
A pharmaceutical composition consisting of a compound selected from the group consisting of ascr #1, ascr #3, ascr #7, ascr #8, ascr #9, and ascr #10;
- a pharmaceutically acceptable carrier;
- and a sugar, a nucleobase, a fatty acid, and/or an amino acid in a dosage form formulated for alleviating an inflammatory or immune disorder.
Dependencies are inferred from the claim text.