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US 12,180,223 B2Granted
3H,4H-thieno[2,3-d]pyrimidin-4-one derivatives as TRPA1 inhibitors
AssigneeBoehringer Ingelheim International GmbH
InventorsFlorian Paul Christian Binder, Jens Willwacher, Martin Thomas Fleck
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Abstract
The present disclosure provides certain 3H,4H-thieno[2,3-d]pyrimidin-4-one derivatives that are inhibitors of transient receptor potential ankyrin 1 (TRPA1), and are therefore useful for the treatment of diseases treatable by inhibition of TRPA1. Also provided are pharmaceutical compositions containing the same, and processes for preparing said compounds.
Claims9
A compound according to formula (I)
- wherein
- A is selected from the group consisting of phenyl, thiophenyl, benzofuranyl and benzothiophenyl, and wherein A is unsubstituted or substituted with one or two members of the group R1 selected from the group consisting of halogen, C1-4-alkyl and O—C1-4-alkyl;
- or a salt thereof.
Dependencies are inferred from the claim text.