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US 12,180,210 B2Granted
Compounds
AssigneeIntra-Cellular Therapies, Inc.
InventorsPeng Li, Hailin Zheng
Life of this patent
Estimating the term…
Abstract
The present disclosure relates to novel PDE2 inhibitory compounds of Formula I as described herein, their use as pharmaceuticals and pharmaceutical compositions comprising them.
Claims20
A Compound of Formula I
- wherein
- (i) R1 and R2 together with the nitrogen atom form an unsubstituted heteroC3-7cycloalkyl;
- (ii) R3 is H or C1-4alkyl;
- (iii) R4 is heteroaryl, halo, cyano or aryl optionally substituted with one or more groups selected from C1-4alkyl, C3-7cycloalkyl, C1-4alkoxy and haloC1-4alkyl;
- (iv) R5 is H or C1-4alkyl;
- (v) R6 is H or C1-4alkyl;
- in free or salt form.
4 more elements
Dependencies are inferred from the claim text.