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US 12,180,204 B1Granted
2-(benzo[d]thiazol-2-yl)-N′-(2-(5-phenyl-1,3,4-oxadiazol-2-ylthio)acetoxy)acetimidamide as an antimicrobial compound
AssigneeKing Faisal University
InventorsHany Mohamed Abd El-Lateef Ahmed, Mai Mostafa Khalaf Ali, Antar Ahmed Abdelhamid Ahmed, Amer A. Amer
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Abstract
A 2-(benzol[d]thiazol-2-yl)-N′-(2-(5-phenyl-1,3,4-oxadiazol-2-ylthio)acetoxy)acetimidamide compound, its synthesis, and its use as an antimicrobial agent.
Claims7
A method of making a 2-(benzo[d]thiazol-2-yl)-N′-(2-(5-phenyl-1,3,4-oxadiazol-2-ylthio)acetoxy)acetimidamide compound, the method comprising:
- adding carbonyldiimidazole (CDI) to a solution of 2-(5-phenyl-1,3,4-oxadiazol-2-ylthio)acetic acid in acetonitrile to obtain a first reaction mixture;
- stirring the first reaction mixture;
- adding 2-(benzo[d]thiazol-2-yl)-N′-hydroxyacetimidamide to the first reaction mixture to obtain a second reaction mixture;
- stirring the second reaction mixture;
- purifying a formed precipitate by filtering and recrystallization from acetonitrile;
- and
- obtaining the 2-(benzo[d]thiazol-2-yl)-N′-(2-(5-phenyl-1,3,4-oxadiazol-2-ylthio)acetoxy)acetimidamide compound.
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