Back to results
US 12,180,196 B2Granted
Azetidine-substituted pyridine and pyrazine compounds as inhibitors of cannabinoid receptor 2
AssigneesHoffmann-La Roche Inc., Eidgenoessische Technische Hochschule Zuerich
InventorsSimon M. Ametamey, Luca Gobbi, Uwe Grether, Julian Kretz
Life of this patent
Estimating the term…
Abstract
The invention relates to a compound of formula (I) wherein A1 and R1-R4 are as defined in the description and in the claims. The compound of formula (I) can be used as a medicament.
Claims10
A compound of formula (I)
- wherein
- A is —CH— or nitrogen;
- R1 is haloalkoxyazetidinyl, halosulfonylazetidinyl, 3-fluoro-3,3-dideuteriopropyloxyazetidinyl, 2-fluoro-2,2-dideuterio-ethyloxyazetidinyl, fluorodideuteriomethoxyazetidinyl, 2-fluoro-2,2-dideuterioethylazetidinyl or fluorodideuteriomethylazetidinyl;
- R2 and R3 are both alkyl at the same time;
- or
- R2 and R3, together with the carbon atom to which they are attached, form oxetanyl;
- and
- R4 is alkoxycarbonyl or aminocarbonylalkyl;
- or a pharmaceutically acceptable salt thereof.
6 more elements
Dependencies are inferred from the claim text.