6-(6-bromo-2-oxo-2H-chromen-3-yl)-4-(2,4-dichlorophenyl)-2-alkoxynicotinonitrile as an antimicrobial compound

Abstract

A 6-(6-bromo-2-oxo-2H-chromen-3-yl)-4-(2,4-dichlorophenyl)-2-alkoxynicotinonitrile compound useful as an antimicrobial agent. A method of making the 6-(6-bromo-2-oxo-2H-chromen-3-yl)-4-(2,4-dichlorophenyl)-2-alkoxynicotinonitrile compound includes adding a mixture of 3-acetyl-2H-1-benzopyran-2-one, 6-bromo-3-(3-(2,4-dichlorophenyl)prop-2-enoyl)-2H-1-benzopyran-2-one and malononitrile to a solution of a sodium alkoxide in an absolute alcohol with stirring to obtain a reaction mixture; irradiating the reaction mixture followed by cooling to room temperature to obtain a crude product; and purifying the crude product by filtering and recrystallization using the absolute alcohol.

Dependencies are inferred from the claim text.