Blood oxygenator
AssigneeUniversity of Maryland, Baltimore
InventorsZhongjun Wu, Bartley P. Griffith
Life of this patent
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Abstract
A blood oxygenator is disclosed comprising a housing, a blood inlet, a blood outlet, a spiral volute, a gas inlet, an oxygenator fiber bundle, and a gas outlet. The housing encloses the fiber bundle and provides the structure for the blood flow path and connectors. The fiber bundle comprises gas-exchange membranes which transfer oxygen to the blood and remove carbon dioxide when the blood flows across the membranes. The spiral volute guides the blood to flow through the fiber bundle. A gas flow chamber receives sweep gas containing oxygen and distributes the sweep gas into the fiber membranes, which gas is then exchanged with the blood being oxygenated.
Claims16
A blood oxygenation system comprising:
- a housing having a top and a bottom;
- a blood inlet located at a bottom of the housing and a blood outlet located at a top of the housing;
- a spiral volute within the housing configured to guide blood from the blood inlet to flow circumferentially around an oxygenator fiber bundle, wherein the oxygenator fiber bundle comprises microporous hollow fibers arranged to form a cylindrical annulus;
- and
- a gas flow chamber configured to distribute oxygen-containing sweep gas into the microporous hollow fibers, wherein the sweep gas facilitates the transfer of oxygen into the blood and the removal of carbon dioxide from the blood.
A compact blood oxygenator for ambulatory use, comprising:
- a cylindrical housing with integrated inlet and outlet ports for blood and gas positioned to facilitate vertical blood flow through the device;
- a blood inlet at the lower end of the housing and a blood outlet at the upper end of the housing;
- a fiber bundle comprising gas-exchange membranes configured to transfer oxygen to the blood and remove carbon dioxide, wherein the fiber bundle is arranged in a cylindrical configuration within the housing;
- and
- a spiral volute configured to direct blood entering through the blood inlet to flow in a helical pattern around the fiber bundle before passing radially inward through the fiber bundle.
A method for oxygenating blood in an ambulatory setting, comprising:
- providing a blood oxygenator comprising a cylindrical housing, a spiral volute, a fiber bundle with gas-exchange membranes, and an integrated heat exchanger;
- introducing blood into the blood oxygenator through a blood inlet at a bottom of the housing;
- directing the blood to flow helically around the fiber bundle via the spiral volute to ensure uniform distribution of blood across the fiber bundle;
- transferring oxygen to the blood and removing carbon dioxide from the blood via the gas-exchange membranes as the blood flows radially through the fiber bundle;
- regulating the temperature of the blood using the integrated heat exchanger before the blood contacts the fiber bundle;
- and
- discharging the oxygenated and temperature-regulated blood from a blood outlet at a top of the housing.
Dependencies are inferred from the claim text.