US 12,178,911 B2Granted

Dry powder formulations of thymic stromal lymphopoietin (TSLP)-binding antibodies and methods of use thereof

AssigneeMedImmune, LLC

InventorsCatherine Eugenie Chaillan Huntington, Susan Hoe, Prakash Manikwar, Roland Wilhelm Kolbeck, Emma Suzanne Cohen, David Lechuga-Ballesteros, Kellisa Beth Hansen, Dexter Joseph D'sa, Saba Ghazvini

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Abstract

The present technology relates generally to dry powder formulations of antibodies specific for thymic stromal lymphopoietin (TSLP), as well as methods of treating asthma, using the dry powder formulations, suitably via pulmonary delivery.

Claims5

Dependent claims

An antigen binding fragment of an anti-TSLP antibody comprising a heavy chain having the sequence set forth in SEQ ID NO:28 and a light chain having the sequence set forth in SEQ ID NO:29, wherein the antigen binding fragment is a Fab derived from IgG1.

Dependencies are inferred from the claim text.

Facts

Application: 18/053,941Filed 9 Nov 2022 · continuation
Priority: 28 Oct 2019
Published: US 2023/0201120 A129 Jun 2023
Granted: 31 Dec 2024
Term ends: Not estimatedThe source records don’t support an estimate.

Classification21 codes

A61K 9/1623
Organic compounds, e.g. phospholipids, fats: sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
A61K 9/0075
Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy: for inhalation via a dry…
A61K 9/145
Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried,…: with…
A61K 9/1652
Organic macromolecular compounds: polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Family

Application62/926,833Us provisional application · filed 28 Oct 2019
Application17/081,821Parent of this continuation · filed 27 Oct 2020
US 2023/0201120 A1Pre-grant publication · published 29 Jun 2023
US 11,904,053 B2Parent of this continuation
US 2021/0121406 A1Published application
US 12,178,911 B2This patent

From the US filing history. Foreign family members aren’t listed.

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