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US 12,178,838 B2Granted
Synthetic neuromodulatory peptides
AssigneeLactocore, Inc.
InventorsAnton Malyshev, Igor Doronin, Gennady Babkin, Askar Kuchumov
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Abstract
A pharmaceutical composition comprising a synthetic neuromodulatory peptide is described. The invention discloses neuromodulatory peptides as defined in the claims and methods of using such molecules for therapeutic application. The neuromodulatory peptides included in the composition have been found to be effective in treatment of depression and other mood disorders, including anxiety.
Claims20
A method for treating a mood disorder, comprising administering to a subject in need thereof a composition comprising a synthetic neuromodulatory peptide defined by the general formula I:
- R1R2R3R4 (I)
- wherein:
- R1 is selected from the amino acids F, W, and D;
- R2 is selected from the amino acids Q, D, and K;
- R3 is selected from the amino acids S, Q, and T;
- and
- R4 is selected from the amino acids E and V;
- and
- the subject in need thereof is diagnosed with the mood disorder.
6 more elements
Dependencies are inferred from the claim text.