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US 12,178,819 B2Granted
DPP IV inhibitor formulations
AssigneeBoehringer Ingelheim International GmbH
InventorsAnja Kohlrausch, Patrick Romer, Gerd Seiffert
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Abstract
The present invention relates to pharmaceutical compositions of DPP IV inhibitors with an amino group, their preparation and their use to treat diabetes mellitus.
Claims20
A pharmaceutical composition comprising as an active ingredient a DPP IV inhibitor compound of formula
- in an amount of 5 mg, or a salt thereof, a first diluent, a second diluent, a binder, a disintegrant and a lubricant, wherein the first diluent is mannitol and the second diluent is pregelatinized starch
- wherein the pharmaceutical composition comprises:
- 0.5-20% by weight of active ingredient
- 40-88% by weight of first diluent,
- 3-40% by weight of second diluent,
- 1-5% by weight of binder,
- 5-15% by weight of disintegrant, and
- 0.1-4% by weight of lubricant.
5 more elements
Dependencies are inferred from the claim text.