Laser eye surgery system calibration

A method implemented in a laser system, comprising:

• providing an object selected from the group consisting of an eye, a fluid of a patient interface above the eye, a calibration apparatus comprising one or more structures similar to a structures of the eye, and a combination thereof, the object including first and second optically transmissive materials having differing indices of refraction;
• by a laser, generating a laser beam;
• by a processor, controlling the laser and an optical delivery system to deliver the laser beam to the object to form a plurality of marks in both the first material and the second material per a plurality of target locations, wherein the marks in the first material and the second material together define a three dimensional calibration volume in the object that includes both the first material and the second material;
• by a measurement system, measuring a plurality of locations of the marks in the first material and the second material;
• and
• by the processor, determining a calibration of the laser system for the calibration volume by comparing the target locations and the measured locations of the marks using the indices of refraction of the first and second materials.

A laser system, comprising:

• a laser configured to generate a laser beam;
• a measurement system configured to measure first and second optically transmissive materials of an object selected from the group consisting of an eye, a fluid of a patient interface above the eye, a calibration apparatus comprising one or more structures similar to a structures of the eye, and a combination thereof, the first and second optically transmissive materials having differing indices of refraction;
• an optical delivery system coupled to the laser to deliver the laser beam to the second material through the first material of the object;
• and
• a processor coupled to the measurement system and the optical delivery system, the processor configured to form a plurality of marks in both the first material and the second material with the laser beam per a plurality of target locations, wherein the marks in the first material and the second material together define a three dimensional calibration volume in the object that includes both the first material and the second material, to measure a plurality of locations of the marks with the measurement system, and to calibrate the system for the calibration volume by comparing the target locations and the measured locations of the marks using the indices of refraction.