A computer-implemented method for facilitating risk assessment of coronary artery disease (CAD) for a subject based on image analysis of one or more medical images of the subject, the computer-implemented method comprising:
- accessing, by a computer system, one or more medical images comprising one or more regions of one or more coronary arteries of a subject;
- performing, by the computer system, a first analysis of the one or more medical images to determine presence of stenosis in the one or more regions of the one or more coronary arteries of the subject;
- performing, by the computer system, a second analysis of the one or more medical images for determination of atherosclerosis in the one or more regions of the one or more coronary arteries, wherein the second analysis comprises:
- identifying one or more regions of plaque in the one or more regions of the one or more coronary arteries of the subject;
- and
- generating one or more quantified plaque parameters based at least in part on the identified one or more regions of plaque, the one or more quantified plaque parameters comprising one or more of total plaque volume, volume of low attenuation plaque, volume of non-calcified plaque, or volume of calcified plaque;
- performing, by the computer system, a third analysis of the one or more medical images for determination of ischemia in the one or more regions of the one or more coronary arteries, wherein the third analysis comprises:
- generating one or more vascular parameters of the one or more regions of the one or more coronary arteries, the one or more vascular parameters comprising one or more of vascular morphology, lumen wall, or vessel wall;
- and
- determining a risk of ischemia for the one or more regions of the one or more coronary arteries based at least in part on the generated one or more vascular parameters;
- receiving, by the computer system, a user request to generate a graphical representation of results of one or more of the first analysis, the second analysis, or the third analysis;
- and
- causing, by the computer system, in response to receiving the user request, display of the graphical representation of results of one or more of the first analysis, the second analysis, or the third analysis, wherein the graphical representation is configured to be further used to facilitate risk assessment of CAD for the subject,
- wherein the graphical representation of results of the second analysis comprises a first graphical user interface comprising a first panel displaying one or more straightened vessel views of at least a portion of a coronary vessel and a second panel displaying a cross-sectional view of the coronary vessel, wherein the first panel and the second panel are configured such that a first selection of a first location in the first panel along the one or more straightened vessel views causes display of the cross-sectional view at the location in the third panel, wherein the cross-sectional view in the second panel comprises color-coding of one or more of low attenuation plaque, non-calcified plaque, or calcified plaque,
- wherein the computer system comprises a computer processor and an electronic storage medium.