Sampling face mask

A sampling face mask for collecting substances exhaled from the nose of a subject, comprising:

• a mask body having a front side conforming to the shape of the nose of the subject, a bottom, and one or more clamping blocks disposed on the bottom;
• a removable cartridge removably coupled to the mask body comprising:
• a cartridge body having a chamber for housing the substances exhaled from the nose of the subject;
• and
• a door disposed above the chamber for opening or closing the chamber, and
• a driving means operably coupled to the mask body, the cartridge body, and the door for driving the door to move laterally or vertically with respect to the cartridge body thereby opening or closing the chamber;
• wherein,
• the one or more clamping blocks of the mask body can hold the door in place thereby keeping the door from closing and the chamber being disposed underneath the nose and stayed open;
• and
• when the one or more clamping blocks does not hold the door in place, the door is driven closed via the driving means thereby closing the chamber, and allowing the removable cartridge to be separated from the mask body.