Systems and methods for determination of blood flow characteristics and pathologies through modeling of myocardial blood supply
AssigneeHeartFlow, Inc.
InventorsLeo Grady, Charles A. Taylor
Life of this patent
Estimating the term…
Abstract
Systems and methods are disclosed for evaluating a patient with vascular disease. One method includes receiving one or more vascular models associated with either the patient or with a plurality of individuals; receiving observed perfusion information associated with the patient; and estimating, using one or more computer processors, one or more blood flow characteristics or one or more pathological characteristics of the patient based on the observed perfusion information and the one or more vascular models.
Claims20
A computer-implemented method of analyzing patient-specific perfusion, the method comprising:
- receiving a patient-specific vascular model associated with an individual;
- receiving or determining a pathology of the patient-specific vascular model;
- receiving a patient-specific tissue model associated with the individual;
- identifying one or more perfusion territories within the patient-specific vascular model, using the patient-specific tissue model;
- parameterizing one or more locations of the pathology within the one or more perfusion territories of the patient-specific vascular model;
- using forward modeling to generate a patient-specific perfusion model by modeling a blood flow through the identified perfusion territories;
- prompting a user to provide a severity of the pathology at the one or more locations;
- and
- assessing an effect of the pathology on perfusion by modeling perfusion through portions of the one or more perfusion territories corresponding to locations of the pathology for which the user provided a severity of the pathology.
A system for analyzing patient-specific perfusion, the system comprising:
- a data storage device storing instructions for generating a patient-specific perfusion treatment recommendation;
- and
- a processor configured to execute the instructions to perform a method including:
- receiving a patient-specific vascular model associated with an individual;
- receiving or determining a pathology of the patient-specific vascular model;
- receiving a patient-specific tissue model associated with the individual;
- identifying one or more perfusion territories within the patient-specific vascular model, using the patient-specific tissue model;
- parameterizing one or more locations of the pathology within the one or more perfusion territories of the patient-specific vascular model;
- using forward modeling to generate a patient-specific perfusion model by modeling a blood flow through the identified perfusion territories;
- prompting a user to provide a severity of the pathology at the one or more locations;
- and
- assessing an effect of the pathology on perfusion by modeling perfusion through portions of the one or more perfusion territories corresponding to locations of the pathology for which the user provided a severity of the pathology.
A non-transitory computer readable medium for use on a computer system containing computer-executable programming instructions for analyzing patient-specific perfusion, the instructions comprising:
- receiving a patient-specific vascular model associated with an individual;
- receiving or determining a pathology of the patient-specific vascular model;
- receiving a patient-specific tissue model associated with the individual;
- identifying one or more perfusion territories within the patient-specific vascular model, using the patient-specific tissue model;
- parameterizing one or more locations of the pathology within the one or more perfusion territories of the patient-specific vascular model;
- using forward modeling to generate a patient-specific perfusion model by modeling a blood flow through the identified perfusion territories;
- prompting a user to provide a severity of the pathology at the one or more locations;
- and
- assessing an effect of the pathology on perfusion by modeling perfusion through portions of the one or more perfusion territories corresponding to locations of the pathology for which the user provided a severity of the pathology.
Dependencies are inferred from the claim text.