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US 12,110,547 B2Granted
Selective surface patterning via nanoimprinting
AssigneeIllumina, Inc.
InventorsAndrew A. Brown, Wayne N. George, Alexandre Richez, M. Shane Bowen
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Abstract
Substrates comprising dual functional polymer layered surfaces and the preparation thereof by using UV nano-imprinting processes are disclosed. The substrates can be used as flow cells, nanofluidic or microfluidic devices for biological molecules analysis.
Claims13
A system, comprising:
- a substrate having a surface;
- a first polymer layer disposed on the substrate surface, wherein the first polymer layer comprises a first plurality of functional groups and further comprises an imprinted pattern of features;
- and
- a second polymer layer disposed over at least a portion of the first polymer layer;
- wherein the first plurality of functional groups provide reactive sites for covalent bonding of a functionalized molecule and the second polymer layer comprises a second plurality of functional groups that differ from the first plurality of functional groups;
- wherein a first region of the system is defined where the first polymer layer is exposed;
- and
- wherein a second region of the system is defined where the second polymer layer is exposed.
5 more elements
Dependencies are inferred from the claim text.