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US 12,110,546 B2Granted
Tertiary amine substituted coumarin compounds and uses as fluorescent labels
AssigneeIllumina Cambridge Limited
InventorsNikolai Nikolaevich Romanov, Patrick McCauley, Niall Hynes
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Abstract
The present application relates to tertiary amine substituted coumarin derivatives and their uses as fluorescent labels. These compounds may be used as fluorescent labels for nucleotides in nucleic acid sequencing applications.
Claims23
A nucleotide defined by the formula:
- wherein B is a nucleobase;
- OR′ is a triphosphate;
- R″ is a 3′ blocking group;
- R′″ is H;
- L is a linker moiety;
- and
- Dye comprises:
4 more elements
Dependencies are inferred from the claim text.