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US 12,110,326 B2Granted
Anti-ILT3 antibodies and antibody drug conjugates
AssigneeBluefin BioMedicine, Inc.
InventorsJaime Rene Darce, Scott Michael Lonning, Nels Eric Pederson, Klarisa Rikova, Aleksandr Tkachev
Life of this patent
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Abstract
Disclosed herein are anti-immunoglobulin-like transcript-3 (ILT3) antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.
Claims22
An isolated antibody, or antigen binding portion thereof, that binds to immunoglobulin-like transcript 3 (ILT3), wherein the antibody, or antigen binding portion thereof, comprises:
- a heavy chain variable region that is at least 95% identical to SEQ ID NO:
- 81 and a light chain variable region that is at least 95% identical to SEQ ID NO:
- 84;
- a heavy chain variable region that is at least 95% identical to SEQ ID NO:
- 1 and a light chain variable region that is at least 95% identical to SEQ ID NO:
- 5;
- a heavy chain variable region that is at least 95% identical to SEQ ID NO:
- 53 and a light chain variable region that is at least 95% identical to SEQ ID NO:
- 57;
- a heavy chain variable region that is at least 95% identical to SEQ ID NO:
- 74 and a light chain variable region that is at least 95% identical to SEQ ID NO:
- 78;
- or
- a heavy chain variable region that is at least 95% identical to SEQ ID NO:
- 104 and a light chain variable region that is at least 95% identical to SEQ ID NO:
- 100.
13 more elements
Dependencies are inferred from the claim text.