Nucleic acid extraction apparatus and method of use thereof

Nucleic acid extraction apparatus, comprising:

• a plurality of nucleic acid extraction chambers;
• a reaction chamber, wherein the reaction chamber is selectively in communication with one of the nucleic acid extraction chambers;
• a hollow piston disposed in the reaction chamber and configured to move between a first position and a second position in the reaction chamber to change a pressure in the reaction chamber;
• a magnetic bead disposed in the reaction chamber for binding a nucleic acid;
• a receiving chamber for accommodating a permanent magnet as to fix the magnetic bead on an outer side wall of the receiving chamber;
• a nucleic acid amplification element, wherein the nucleic acid amplification element is a nucleic acid amplification chamber that is in fluidic communication with the reaction chamber;
• wherein the receiving chamber is disposed in the hollow piston, and the hollow piston is movable relative to the receiving chamber;
• and wherein a recess is provided on the outer side wall at a bottom of the hollow piston, and when the hollow piston is at the second position, the recess and the outer side wall of the receiving chamber form a space for accommodating the magnetic bead therein.