Agent delivery devices

A medical device comprising:

• a handle including an actuator;
• and
• a sheath extending from the handle, wherein a distal portion of the sheath includes:
• a first chamber including a first agent;
• a second chamber including a second agent;
• a tube disposed within the first chamber, wherein the tube has an internal lumen defining the second chamber, and wherein a wall of the tube includes a plurality of holes;
• and
• at least one actuation element is configured to transmit a force from the actuator to each of a first piston received within the first chamber and a second piston received within the second chamber;
• wherein each of the plurality of holes is configured to isolate the first agent from the second agent in the second chamber when the at least one actuation element receives no force and to release the second agent from the second chamber through the plurality of holes to mix with the first agent when the at least one actuation element receives the force.

A medical device comprising:

• a handle including an actuator;
• a sheath extending from the handle, wherein the sheath includes:
• a first chamber including a first agent and a second chamber including a second agent, wherein each of the first chamber and the second chamber is disposed in a distal portion of the sheath;
• and
• a first piston received within the first chamber and a second piston received within the second chamber;
• and
• a tube configured to transmit a force from the actuator to at least one of the first piston and the second piston,
• wherein the second chamber is defined by a first tube disposed within the first chamber,
• wherein a wall of the first tube includes a plurality of holes, each of the plurality of holes has a sufficiently small diameter and has a sufficient length through the wall of the tube such that the second agent does not pass through the plurality of holes until a force is exerted by the second piston,
• wherein a distalmost end of the first tube is proximal of an opening in a distalmost end of the sheath, the opening of the distalmost end of the sheath being coaxial with the first and second chambers.