Medication infusion devices, systems, and methods

An apparatus for in-situ mixing, the apparatus comprising:

• a patient access subassembly;
• a first fluid reservoir comprising a first fluidic substance;
• a second fluid reservoir comprising a second fluidic substance, wherein the second fluidic substance comprises a medicament;
• a base fluidically coupled to the patient access subassembly, the first fluid reservoir, and the second fluid reservoir;
• and
• an assembly comprising a processor adapted to control the base to:
• receive a blood product from a patient;
• mix the blood product with the first fluidic substance to form a third fluidic substance;
• mix the third fluidic substance with the second fluidic substance to form a fourth fluidic substance;
• and
• transfer the fourth fluidic substance to the patient access subassembly to expel the fourth fluidic substance from the patient access subassembly and back into the patient,
• wherein the apparatus is configurable such that fluidic communication is achievable between any of the first fluid reservoir, the second fluid reservoir, and the patient access subassembly.