Materials architecture for gastric residence systems

A co-extruded elongate member comprising:

• at least two segments, each segment comprising a proximal end, a distal end, and an outer surface therebetween;
• and
• a reinforcing material comprising one or more of polycaprolactone (PCL), polydioxanone, polylactic acid, polycarbonate, polyether ether ketone, polyethylene, or polypropylene,
• wherein the at least two segments are attached together via a linker region comprising a disintegrating linker comprising PCL, wherein the at least one disintegrating linker is a time-dependent linker and is configured to weaken to cause the elongate member to decouple or weaken, and
• wherein the reinforcing material extends axially along one or more of the at least two segments,
• wherein said elongate member is configured for use in a stellate gastric residence system having a gastric residence time between about 48 hours and one month.