Systems, methods and products for minimizing tissue reactions and tissue injury at an infusion site
AssigneeCell and Molecular Tissue Engineering, LLC
InventorsUlrike W. Klueh, Donald L Kreutzer
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Abstract
Products, systems and methods are disclosed for lowering the concentrations of at least one of preservatives and fibrils in a liquid insulin composition. One method comprises replacing at least a portion of at least one of phenol and m-cresol with at least one of cyclodextrins, cyclodextrin polymers, cyclodextrin beads, and an ion exchange resin.
Claims16
A method of lowering the concentrations of preservatives in a liquid insulin composition delivered through a transdermal insulin pump system, the preservatives including at least one of phenol and m-cresol, the method comprising filtering the liquid insulin composition by incorporating into the insulin pump system a filter comprising a cyclodextrin configured to remove phenol and m-cresol without removing insulin.
Dependencies are inferred from the claim text.