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US 12,109,229 B2Granted
Treatment of neurodegenerative disease with sodium chlorite
AssigneesNeuvivo, Inc., The Regents of the University of California
InventorsVernon A. Norviel, Michael S. McGrath
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Abstract
The present invention provides a method of treating frontotemporal dementia, or a childhood genetic neurodegenerative disease such as Ataxia Telangiectasia (A-T), or neurodegenerative diseases such as Parkinson's disease or neuropsychiatric diseases comprising administering to a subject in need thereof an effective amount of chlorite composition, such as sodium chlorite. The present invention thereby provides a method of modulating the immune system in a subject in need thereof. Described herein are methods of administration and treatment.
Claims14
A method comprising:
- a) administering to a subject who has dementia a regimen of sodium chlorite;
- and
- b) monitoring a plasma level of C-reactive protein in the subject during the regimen of sodium chlorite and determining based on the monitoring that the plasma level of C-reactive protein in the subject is at least 1125 ng/mL.
Dependencies are inferred from the claim text.