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US 12,109,197 B2Granted
Combinations of β-lactam compounds and probenecid and uses thereof
AssigneeIterum Therapeutics International Limited
InventorMichael Dunne
Life of this patent
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Abstract
The present disclosure relates to combinations of a β-lactam compound or a pharmaceutically acceptable salt thereof and probenecid or a pharmaceutically acceptable salt thereof. The present disclosure also relates to methods of treating or preventing a disease via administering to subjects in need thereof a β-lactam compound or a pharmaceutically acceptable salt thereof and probenecid or a pharmaceutically acceptable salt thereof.
Claims10
A method of treating or preventing uncomplicated urinary tract infection, comprising:
- administering to a subject in need thereof from 400 mg to 600 mg of a β-lactam compound or a pharmaceutically acceptable salt thereof, and from 400 mg to 600 mg of probenecid or a pharmaceutically acceptable salt thereof, simultaneously twice daily for from 5 days to 10 days,
- wherein the β-lactam compound is:
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.