Compositions and methods for treatment of vaginal infections
AssigneeVireo Systems, Inc.
InventorsMark C. Faulkner, Deeannah Seymour
Life of this patent
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Abstract
Compositions and methods for treatment and prevention of vaginal infections where the compositions include creatinine, such as protonated creatinine or creatinine salts, and optionally one or more weak acids, such as boric acid. The compositions may be used to treat and/or prevent a vaginal infection, such as bacterial vaginosis, to prevent recurrence of a vaginal infection, to treat and/or prevent a sexually transmitted disease (STD) or sexually transmitted infection (STI), and reduce the incidence and/or risk of a subject transmitting a STI or STD.
Claims15
A method for inhibiting growth of one or more species of bacteria associated with bacterial vaginosis, comprising:
- preparing a composition consisting of protonated creatinine, a protonated creatinine salt, or combinations thereof, wherein the protonated creatinine, protonated creatinine salt, or combination thereof is present in the composition in an amount of about 10 mg to about 300 mg;
- and
- subjecting the one or more species of bacteria to the composition.
A method for killing one or more species of bacteria associated with bacterial vaginosis, comprising:
- preparing a composition consisting of protonated creatinine, a protonated creatinine salt, or combinations thereof, and a weak acid, wherein the protonated creatinine, protonated creatinine salt, or combination thereof is present in the composition in an amount of about 10 mg to about 300 mg and the weak acid is present in the composition in an amount of about 500 mg to about 700 mg;
- and
- subjecting the one or more species of bacteria to the composition.
A method for inhibiting growth of Gardnerella vaginalis, Mobiluncus mulieris, or a combination thereof, comprising:
- preparing a composition consisting of (i) a protonated creatinine, a protonated creatinine salt, or combinations thereof, (ii) a weak acid, and (iii) a probiotic, prebiotic, or combinations thereof, wherein the protonated creatinine, protonated creatinine salt, or combination thereof is present in the composition in an amount of about 10 mg to about 300 mg and the weak acid is present in the composition in an amount of about 500 mg to about 700 mg;
- and
- subjecting the Gardnerella vaginalis, Mobiluncus mulieris, or a combination thereof to the composition.
Dependencies are inferred from the claim text.