Lidocaine patch and methods of use thereof
OwnerJames Ciulloinventor
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Abstract
This invention is directed to a transdermal delivery patch comprising local anesthetic agent and optionally a permeation enhancement agent for reducing neuropathic pain.
Claims6
A method for reducing pain from degenerative bone disease in a subject comprising applying on a skin surface of the subject a patch for transdermal delivery of lidocaine consisting of a low dose of a therapeutically effective amount of lidocaine and an adhesive that acts as a pharmaceutically acceptable carrier, a permeation enhancer and an excipient wherein said active ingredient consists of 3.6 percent to less than 5 percent lidocaine by weight and wherein said pain from degenerative bone disease consists of pain from microarchitectural deterioration of bone tissue.
A method for reducing pain from degenerative bone disease in a subject comprising applying on a skin surface of the subject a patch for transdermal delivery of lidocaine consisting of a low dose of a therapeutically effective amount of an active ingredient and an adhesive that acts as a pharmaceutically acceptable carrier, a permeation enhancer and an excipient wherein said active ingredient consists of 3 to less than 4 percent lidocaine by weight and wherein said pain from degenerative bone disease consists of pain from low bone mass.
A method for reducing pain from low bone mass in a subject without an injection comprising, applying on a skin surface of a subject a patch for transdermal delivery of lidocaine consisting of a low dose of a therapeutically effective amount of an active ingredient and an adhesive that acts as a pharmaceutically acceptable carrier, and a permeation enhancer, and an excipient;
- wherein pain from low bone mass consists of chronic back pain and wherein said low dose of the therapeutically effective amount of said active ingredient consists of less than 5 percent lidocaine by weight.
Dependencies are inferred from the claim text.