Transseptal delivery system

A delivery system for delivering a prosthesis to a target treatment area, the system comprising:

• an inner guidewire catheter having a proximal end, a distal end, and a lumen extending therebetween, the lumen sized to slidably receive a guidewire;
• a distal capsule coupled to the distal end of the inner guidewire catheter, wherein the distal capsule comprises an inner channel sized to receive the prosthesis;
• a bell catheter slidably disposed over the inner guidewire catheter, the bell catheter having a bell element adjacent a distal end of the bell catheter;
• an anchor catheter slidably disposed over the bell catheter, the anchor catheter having an anchor element adjacent a distal end of the anchor catheter and configured to engage the prosthesis, and wherein the bell element constrains the prosthesis into engagement with the anchor element;
• a sheath catheter slidably disposed over the anchor catheter, the sheath catheter having a proximal end and a distal end;
• and
• an actuator mechanism comprising a first rotational actuator element, wherein the first rotational actuator element is operably coupled to both the inner guidewire catheter and the bell catheter, wherein actuation of the first rotational actuator element in a first direction moves the distal capsule proximally, and wherein actuation of the first rotational actuator element in a second direction opposite the first direction moves the distal capsule distally and moves the bell element away from the anchor element thereby removing a constraint from the prosthesis and allowing the prosthesis to expand.