Back to results
US 12,060,393 B2Granted
Vaccine and methods for detecting and preventing filariasis
AssigneeThe Bd of Trustees of the University of Illinois
InventorRamaswamy Kalyanasundaram
Life of this patent
Estimating the term…
Abstract
The present invention is a multivalent vaccine for immunizing an animal against filariasis. In some embodiments, the antigens of the multivalent vaccine are protein-based, DNA-based, or a combination thereof. This invention also provides a method and kit for detecting a filarial nematode and determining vaccine efficacy.
Claims3
A method for immunizing an animal against filariasis administering to an animal in need thereof a vaccine comprising
- (a) Brugia malayi Abundant Larval Transcript protein comprising SEQ ID NO:
- 78;
- and
- (b) a Brugia malayi Small heat shock protein 12.6 comprising SEQ ID NO:
- 81;
- a Brugia malayi Tetraspanin protein comprising SEQ ID NO:
- 82;
- a Brugia malayi Thioredoxin Peroxidase 2 protein comprising SEQ ID NO:83, or a combination thereof,
- wherein each of the proteins of (a) and (b) elicits an immune response in an animal thereby immunizing the animal against filariasis.
6 more elements
Dependencies are inferred from the claim text.