Chromosomal enhancement and automatic detection of chromosomal abnormalities using chromosomal ideograms

A computer-implemented method for detecting chromosomal abnormalities cryptic deletions or putative cryptic deletions comprising:

• obtaining an image of a banding pattern of a chromosome comprising a cryptic deletion or putative cryptic deletion,
• converting the image into an ideogram depicting said banding pattern,
• comparing the ideogram to an ideogram of an image of a paired control chromosome not comprising the cryptic deletion or putative cryptic deletion, and
• identifying a difference in a banding pattern between the ideogram of the chromosome and the ideogram of the paired control chromosome,
• wherein said difference indicates a cryptic deletion or putative cryptic deletion in the imaged chromosome.