System for determining a tissue-specific property

A system for determining a tissue-specific property in a region of interest of a patient, comprising:

• a memory;
• and
• one or more processors coupled with the memory and configured to:
• provide at least two images of the region of interest, wherein the provided images correspond to different states of the region of interest, and wherein the region of interest comprises different tissue types;
• elastically register the at least two provided images to each other based on image characteristics of the at least two provided images, wherein the registration results in determining at least one elastic registration output allowing to align the at least two provided images with each other;
• determine a specific tissue region that is defined by a specific tissue type and that is in the region of interest in at least one of the provided images, wherein the specific tissue region comprises all parts of the respective provided image that correspond to the specific tissue type;
• determine a specific elastic registration output for the specific tissue region based on the at least one determined elastic registration output;
• and
• determine an elastic indicator for the specific tissue type based on the specific elastic registration output of the specific tissue region, wherein the elastic indicator is indicative of an elastic property of the specific tissue type.